Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600619 | 0.94 | SMN1; SMN2 (0.42) | PPOXCSNK2A1GLASMN1; SMN2MEN1 | |
| SCHEMBL8603664 | 0.92 | SMN1; SMN2 (0.40) | PPOXGLASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8602412 | 0.88 | PPOX (0.38) | PPOXSMN1; SMN2ALDH1A1MAPTCYP2C19 | |
| SCHEMBL3990961 | 0.87 | CSNK2A1 (0.42) | PPOXCSNK2A1GLASMN1; SMN2MEN1 | |
| SCHEMBL9620179 | 0.86 | PPOX (0.42) | PPOXCSNK2A1GLASMN1; SMN2MEN1 | |
| SCHEMBL8599287 | 0.84 | L3MBTL1 (0.48) | PPOXHTTRECQLALDH1A1MAPT | |
| SCHEMBL8603005 | 0.82 | NR1I2 (0.39) | — | |
| SCHEMBL10574907 | 0.82 | GLA (0.41) | PPOXCSNK2A1GLASMN1; SMN2HTT | |
| SCHEMBL8601232 | 0.81 | TLR8 (0.32) | — | |
| SCHEMBL8599741 | 0.81 | CUL4A (0.35) | HTTRECQLALDH1A1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |