SCHEMBL8599773

SCHEMBL8599773

CNC(=O)c1ccc(O)c(C(=O)S)c1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 3/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC2 Q92769 1/20 0.46
THRB P10828 1/20 0.44
PLAU P00749 1/20 0.44
CA2 P00918 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PLK1 P53350 6/20 0.42
TOP1 P11387 2/20 0.41
EGFR P00533 1/20 0.39
MMP13 P45452 1/20 0.39
TERT O14746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8599779 0.81 HDAC6 (0.44) HDAC6HDAC8HDAC2THRBPLAU
SCHEMBL3183606 0.79 PKM (0.52) CA2HTT
SCHEMBL328702 0.79 HDAC6 (0.67) HDAC6HDAC8HDAC2THRBPLAU
SCHEMBL27780497 0.76 NEU3 (0.54) HDAC6HDAC8HDAC2THRBCA2
SCHEMBL21884580 0.76 PLAU (0.53) HDAC6HDAC8HDAC2THRBPLAU
SCHEMBL12218136 0.76 HDAC6 (0.50) HDAC6HDAC8HDAC2THRBPLAU
SCHEMBL16521645 0.75 HDAC8 (0.54) HDAC6HDAC8HDAC2THRBPLAU
SCHEMBL10759595 0.74 HDAC8 (0.64) HDAC6HDAC8HDAC2PLAUCA2
SCHEMBL12100712 0.74 HDAC6 (0.53) HDAC6HDAC8HDAC2THRBPLAU
SCHEMBL8515075 0.74 ESRRG (0.50) HDAC6HDAC8HDAC2THRBPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598241-B1 Lithographic printing material FUJI PHOTO FILM CO LTD (JP) 1998-02-04 EP disclosed
US-5387483-A Developer containing silver halide solvent and hydroquinone; has pH up to 11.8 FUJI PHOTO FILM CO., LTD. (JP) 1995-02-07 US disclosed
EP-0610936-A2 Lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-08-17 EP disclosed
EP-0601600-A2 Processing of lithographic printing material and developer used therein FUJI PHOTO FILM CO., LTD. (JP) 1994-06-15 EP disclosed
EP-0598241-A1 Lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-05-25 EP disclosed