Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.67 |
| ▸ | TOP1 | P11387 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783904 | 0.88 | SIRT1 (0.64) | HDAC6TOP1CA2CA12CA1 | |
| SCHEMBL27828053 | 0.86 | HDAC6 (0.72) | HDAC6TOP1CA2CA12CA1 | |
| SCHEMBL23067301 | 0.83 | HDAC6 (0.62) | HDAC6TOP1CA2CA12CA1 | |
| SCHEMBL29557094 | 0.83 | HDAC6 (0.62) | HDAC6TOP1CA2CA12CA1 | |
| SCHEMBL13495800 | 0.83 | HDAC6 (0.53) | HDAC6TOP1CA2POLBHDAC8 | |
| SCHEMBL12218136 | 0.83 | HDAC6 (0.50) | HDAC6TOP1CA2HDAC8HDAC2 | |
| SCHEMBL4362534 | 0.82 | HDAC6 (0.72) | HDAC6TOP1CA2CA12CA1 | |
| SCHEMBL2662442 | 0.82 | HSP90AA1 (0.53) | HDAC6CA2KDM4EMAPTHDAC8 | |
| SCHEMBL12100712 | 0.82 | HDAC6 (0.53) | HDAC6TOP1CA2MAPTHDAC8 | |
| SCHEMBL22323667 | 0.82 | HDAC6 (0.53) | HDAC6TOP1CA2MAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438052-A | Cephalosporin derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-08-01 | — | — | US | claimed |
| EP-4077507-B1 | PROCESS FOR FRAGMENTING A POLYMER | SPECIALTY OPERATIONS FRANCE (FR) | 2026-04-22 | — | — | EP | disclosed |
| US-12479968-B2 | Process for fragmenting a polymer | SPECIALTY OPERATIONS FRANCE (FR) | 2025-11-25 | — | — | US | disclosed |
| US-20230040771-A1 | PROCESS FOR FRAGMENTING A POLYMER | RHODIA OPERATIONS (FR) | 2023-02-09 | — | — | US | disclosed |
| US-20220396595-A1 | A METAL COMPLEX AND USE THEREOF | RHODIA OPERATIONS (FR) | 2022-12-15 | — | — | US | disclosed |
| CN-114829473-A | Method for breaking polymers | 罗地亚经营管理公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114599772-A | Metal complexes and their use | 罗地亚经营管理公司 | 2022-06-07 | — | — | CN | disclosed |
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2017-10-05 | — | — | US | disclosed |
| US-9334289-B2 | Cephem compound having catechol or pseudo-catechol structure | SHIONOGI & CO., LTD. (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LTD (GB) | 2015-10-22 | — | — | US | disclosed |
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| US-8258290-B2 | Glycomimetic inhibitors of the PA-IL lectin, PA-IIL lectin or both the lectins from pseudomonas | GLYCOMIMETICS, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| WO-2012032085-A1 | SYNTHESIS OF TRIVALENT FLEXIBLE FRAMEWORKS WITH LIGANDS COMPRISING CATECHOL UNITS FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032084-A1 | SYNTHESIS OF TRIPODAL CATECHOL DERIVATIVES HAVING AN ADAMANTYL BASIC FRAMEWORK FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| EP-2428502-A1 | Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces | Justus-Liebig-Universität Gießen (DE) | 2012-03-14 | — | — | EP | disclosed |
| EP-2295442-A2 | Inhibitors of interleukin-1beta converting enzyme | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-03-16 | — | — | EP | disclosed |
| US-20100041626-A1 | GLYCOMIMETIC INHIBITORS OF THE PA-IL LECTIN, PA-IIL LECTIN OR BOTH THE LECTINS FROM PSEUDOMONAS | GLYCOMIMETICS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-7517980-B2 | Glycomimetric inhibitors of the PA-IL lectin, PA-IIL lectin or both the lectins from Pseudomonas | GLYCOMIMETICS, INC. (US) | 2009-04-14 | — | — | US | disclosed |
| US-5438052-A | Cephalosporin derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041626-A1 | GLYCOMIMETIC INHIBITORS OF THE PA-IL LECTIN, PA-IIL LECTIN OR BOTH THE LECTINS FROM PSEUDOMONAS | MASP2, SERPINB1, SIGLEC7 | HDAC6 1698/4885TOP1 4659/4885CA2 2046/4885 |
| US-20220396595-A1 | A METAL COMPLEX AND USE THEREOF | SOD1, MPO, GPX4 | HDAC6 959/4885TOP1 4160/4885CA2 430/4885 |
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | CEP170, CES2, CMBL | HDAC6 1417/4885TOP1 421/4885CA2 521/4885 |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | CEP170, ABL1, CEPT1 | HDAC6 1152/4885TOP1 1125/4885CA2 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.