Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520118 | 0.88 | F10 (0.46) | FAAHF10KMT2AMEN1FFAR1 | |
| SCHEMBL1395777 | 0.87 | FFAR1 (0.56) | FAAHF10PPARGPPARAFFAR1 | |
| SCHEMBL7558282 | 0.83 | FFAR1 (0.55) | FAAHF10FFAR1HTTALDH1A1 | |
| SCHEMBL1533677 | 0.80 | ALOX5 (0.53) | KMT2AMEN1ALDH1A1ALOX5 | |
| SCHEMBL922831 | 0.79 | AGXT (0.52) | FAAHHTTSMN1; SMN2ALDH1A1ALOX5 | |
| SCHEMBL5282643 | 0.79 | F10 (0.48) | FAAHF10FFAR1LMNAHTT | |
| SCHEMBL30381210 | 0.77 | SLC7A5 (0.55) | PPARGPPARA | |
| SCHEMBL5110394 | 0.77 | SLC7A5 (0.55) | PPARGPPARA | |
| SCHEMBL27320423 | 0.76 | PARP10 (0.73) | SIRT2SIRT1SIRT3FAAHF10 | |
| SCHEMBL1326762 | 0.76 | CTBP2 (0.60) | KMT2AMEN1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763523-B1 | NAPHTHALENE DERIVATIVE | TEIJIN LTD (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0763523-A1 | NAPHTHALENE DERIVATIVE | TEIJIN LIMITED (JP) | 1997-03-19 | — | — | EP | disclosed |