Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 8/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604042 | 0.92 | ALDH1A1 (0.47) | TSHRALDH1A1SMN1; SMN2GAAPPARG | |
| SCHEMBL8602959 | 0.91 | TSHR (0.44) | TSHRPPARGCCKBR | |
| SCHEMBL8604456 | 0.90 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2PPARGTP53 | |
| SCHEMBL8603793 | 0.86 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2PPARGTP53 | |
| SCHEMBL8604584 | 0.84 | KDM4E (0.45) | TSHRALDH1A1SMN1; SMN2PPARGTP53 | |
| SCHEMBL8602935 | 0.83 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2PPARGTP53 | |
| SCHEMBL8600322 | 0.83 | TSHR (0.42) | TSHRPPARGTP53 | |
| SCHEMBL8594197 | 0.81 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8554869 | 0.80 | TP53 (0.45) | TSHRALDH1A1SMN1; SMN2PPARGTP53 | |
| SCHEMBL8555357 | 0.80 | PPARG (0.46) | TSHRALDH1A1SMN1; SMN2PPARGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |