Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 16/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604513 | 0.92 | TSHR (0.44) | TSHRHTTPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8602959 | 0.92 | TSHR (0.44) | TSHRHTTPPARG | |
| SCHEMBL8604042 | 0.91 | ALDH1A1 (0.47) | TSHRPPARGALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8555379 | 0.88 | PPARG (0.48) | TSHRHTTPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8604456 | 0.88 | TSHR (0.45) | TSHRPPARGALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8600322 | 0.86 | TSHR (0.42) | TSHRHTTPPARGTP53 | |
| SCHEMBL7465291 | 0.85 | TSHR (0.46) | TSHRHTTPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8599845 | 0.83 | TSHR (0.46) | TSHRPPARGALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8603793 | 0.83 | ALDH1A1 (0.45) | TSHRPPARGALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8556015 | 0.81 | HTT (0.53) | TSHRHTTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |