Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694619 | 0.89 | GNRHR (0.38) | GNRHRCACNA1B | |
| SCHEMBL8697449 | 0.81 | CACNA1B (0.40) | GNRHRCACNA1B | |
| SCHEMBL8697442 | 0.79 | CACNA1B (0.39) | GNRHRCACNA1B | |
| SCHEMBL8694057 | 0.72 | CACNA1B (0.38) | GNRHRCACNA1B | |
| SCHEMBL8694052 | 0.72 | GNRHR (0.38) | GNRHRCACNA1B | |
| SCHEMBL8166907 | 0.64 | CACNA1B (0.72) | GNRHRCACNA1B | |
| SCHEMBL9348378 | 0.62 | NAMPT (0.44) | — | |
| Hydrochloric Acid SCHEMBL6979576 | 0.62 | GNRHR (0.60) | GNRHR | |
| SCHEMBL3277652 | 0.62 | GNRHR (0.65) | GNRHR | |
| SCHEMBL20699701 | 0.61 | GABRG2 (0.39) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849764-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0871624-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997021703-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-06-19 | — | — | WO | disclosed |