Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | DAGLB | Q8NCG7 | 2/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968701 | 0.85 | USP2 (0.51) | CYP17A1USP2LMNACYP2C9CYP2C19 | |
| SCHEMBL4781274 | 0.85 | HDAC3 (0.48) | LMNACYP1A2MEN1KMT2ACHRM2 | |
| SCHEMBL31403206 | 0.84 | TRPM8 (0.40) | NAMPTMEN1KMT2AHCRTR2HDAC3 | |
| SCHEMBL7337070 | 0.82 | CYP17A1 (0.43) | CYP17A1CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL11853062 | 0.82 | NAMPT (0.44) | NAMPTUSP2LMNACYP2C9CYP2C19 | |
| SCHEMBL26148108 | 0.80 | TSHR (0.40) | TSHRHSD17B10HDAC3HDAC1HDAC2 | |
| SCHEMBL13188656 | 0.80 | CYP4A11 (0.51) | LMNACYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL20862455 | 0.76 | MAOA (0.40) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10084755 | 0.76 | MTNR1A (0.52) | CYP2C9CYP2C19CYP1A2CYP3A4MEN1 | |
| SCHEMBL4453600 | 0.76 | LTB4R (0.55) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338738-A | Cerebral function enhancers: acyclic amide derivatives of pyrimidinylpiperidines | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-08-16 | — | — | US | disclosed |