Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814225 | 0.74 | LMNA (0.60) | NFE2L2MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14107685 | 0.74 | LMNA (0.60) | NFE2L2MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL30022725 | 0.74 | NFE2L2 (0.53) | NFE2L2RAB9AMAPTARKDM4E | |
| SCHEMBL6793789 | 0.74 | NFE2L2 (0.53) | NFE2L2RAB9AMAPTARKDM4E | |
| SCHEMBL6793792 | 0.74 | NFE2L2 (0.53) | NFE2L2RAB9AMAPTARKDM4E | |
| SCHEMBL65190 | 0.72 | TDO2 (0.58) | NFE2L2ALDH1A1KDM4EEGFRCYP2C19 | |
| SCHEMBL14086377 | 0.72 | TDO2 (0.58) | NFE2L2ALDH1A1KDM4EEGFRCYP2C19 | |
| SCHEMBL29535211 | 0.72 | TDO2 (0.58) | NFE2L2ALDH1A1KDM4EEGFRCYP2C19 | |
| SCHEMBL65191 | 0.72 | TDO2 (0.58) | NFE2L2ALDH1A1KDM4EEGFRCYP2C19 | |
| SCHEMBL13776889 | 0.72 | NFE2L2 (0.56) | NFE2L2RAB9AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998033765-A1 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |