Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602050 | 0.92 | GAA (0.38) | TSHRGAAPPARGMAPTCTDSP1 | |
| SCHEMBL8601739 | 0.78 | HTT (0.46) | GAAPPARGMAPTBTN3A1ALDH1A1 | |
| SCHEMBL10390030 | 0.70 | TSHR (0.51) | TSHRGAAPPARGALDH1A1HPGD | |
| SCHEMBL10389728 | 0.69 | PPARG (0.49) | TSHRGAAPPARGALDH1A1HPGD | |
| SCHEMBL8601740 | 0.67 | ALDH1A1 (0.47) | GAAPPARGMAPTALDH1A1HPGD | |
| SCHEMBL8604539 | 0.67 | ALDH1A1 (0.42) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL8604551 | 0.66 | KDM4E (0.42) | TSHRMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL8601737 | 0.66 | GAA (0.48) | GAAPPARGMAPTALDH1A1HPGD | |
| SCHEMBL6707311 | 0.66 | TSHR (0.47) | TSHRGAAPPARGALDH1A1HPGD | |
| SCHEMBL6447404 | 0.66 | BTN3A1 (0.44) | TSHRMAPTBTN3A1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |