Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603717 | 0.83 | BTN3A1 (0.39) | ALDH1A1BTN3A1HPGD | |
| SCHEMBL8603619 | 0.80 | SLC6A2 (0.43) | GAAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL8604551 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL8600127 | 0.78 | TSHR (0.41) | GAAPPARGMAPTALDH1A1MEN1 | |
| SCHEMBL8602013 | 0.77 | KMT2A (0.41) | MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL8602050 | 0.76 | GAA (0.38) | GAAPPARGMAPTALDH1A1BTN3A1 | |
| SCHEMBL8603456 | 0.76 | LMNA (0.37) | GAAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL8601737 | 0.74 | GAA (0.48) | HTTGAAPPARGMAPTALDH1A1 | |
| SCHEMBL8601740 | 0.72 | ALDH1A1 (0.47) | HTTGAAPPARGMAPTALDH1A1 | |
| SCHEMBL8603469 | 0.72 | GAA (0.52) | HTTGAAPPARGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |