Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816451 | 0.87 | LMNA (0.37) | SMN1; SMN2LMNAMEN1NPC1HTT | |
| SCHEMBL7816453 | 0.87 | LMNA (0.37) | SMN1; SMN2LMNAMEN1NPC1HTT | |
| SCHEMBL7671498 | 0.77 | LMNA (0.41) | SMN1; SMN2LMNAMEN1NPC1HTT | |
| SCHEMBL7666981 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2LMNAMEN1NPC1HTT | |
| SCHEMBL7667879 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMEN1NPC1HTT | |
| SCHEMBL8067458 | 0.73 | PTGER1 (0.38) | MEN1KMT2APTGER1CYP1A2 | |
| SCHEMBL8067463 | 0.73 | PTGER1 (0.38) | MEN1KMT2APTGER1CYP1A2 | |
| SCHEMBL7816449 | 0.72 | ATM (0.36) | SMN1; SMN2LMNAMEN1NPC1HTT | |
| SCHEMBL7813030 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2LMNAMEN1NPC1HTT | |
| SCHEMBL7665571 | 0.72 | ATM (0.36) | SMN1; SMN2LMNAMEN1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847391-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1998-06-17 | — | — | EP | disclosed |