Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 17/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067463 | 1.00 | PTGER1 (0.38) | PTGER1CYP1A2MEN1KMT2ACCR5 | |
| SCHEMBL8063285 | 0.89 | MEN1 (0.43) | PTGER1CYP1A2MEN1KMT2ACCR5 | |
| SCHEMBL7816453 | 0.86 | LMNA (0.37) | PTGER1CYP1A2MEN1KMT2ACCR5 | |
| SCHEMBL7816451 | 0.86 | LMNA (0.37) | PTGER1CYP1A2MEN1KMT2ACCR5 | |
| SCHEMBL7662551 | 0.86 | HPGD (0.42) | PTGER1CYP1A2MEN1KMT2APTGDR2 | |
| SCHEMBL7666905 | 0.85 | LMNA (0.43) | PTGER1CYP1A2MEN1KMT2APTGDR2 | |
| SCHEMBL7963014 | 0.84 | HCAR3 (0.45) | CCR5 | |
| SCHEMBL7963017 | 0.84 | HCAR3 (0.45) | CCR5 | |
| SCHEMBL7670592 | 0.84 | ALDH1A1 (0.43) | PTGER1CYP1A2MEN1KMT2APTGDR2 | |
| SCHEMBL4868816 | 0.83 | PTGER1 (0.54) | PTGER1CYP1A2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100258-A | 6-(N-(5-BROMO-2-(2-METHYLPROP-2-EN-1-YLOXY)BENZYL)-N -ETHYLAMINO)-PYRIDAZIN-3-YLCARBOXYLIC ACID, AND OTHER 3,6-DISUBSTITUTED PYRIDAZINE DERIVATIVES OF SPECIFIED FORMULA; RELIEVING PAIN | ZENECA LIMITED (GB) | 2000-08-08 | — | — | US | claimed |