Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095943 | 0.85 | GRM2 (0.34) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL5429652 | 0.83 | ALDH1A1 (0.46) | FGFR1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL8512808 | 0.83 | CYP1A2 (0.49) | ALDH1A1KDM4EHPGDLMNACYP3A4 | |
| SCHEMBL8599942 | 0.79 | KMT2A (0.46) | ALDH1A1KDM4EHPGDLMNAGAA | |
| SCHEMBL8599049 | 0.77 | FGFR1 (0.42) | FGFR1KDM4EL3MBTL1TP53 | |
| SCHEMBL8601685 | 0.77 | ALPL (0.42) | ALDH1A1KDM4EHPGDGAACYP3A4 | |
| SCHEMBL27968960 | 0.75 | FGFR1 (0.41) | FGFR1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL20588792 | 0.75 | ALDH1A1 (0.40) | FGFR1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL31095270 | 0.75 | ALDH1A1 (0.40) | FGFR1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5433545 | 0.74 | KDM4E (0.46) | FGFR1ALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |