Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562791 | 0.86 | PIK3C2B (0.41) | KDM4EALDH1A1HPGDMAPTAPEX1 | |
| Trifluoroacetic Acid SCHEMBL8603670 | 0.84 | ALDH1A1 (0.43) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8600049 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL8600493 | 0.83 | DCTPP1 (0.44) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8648411 | 0.83 | ALDH1A1 (0.45) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8603673 | 0.82 | ALDH1A1 (0.45) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8602280 | 0.81 | KDM4E (0.41) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8598184 | 0.81 | PPARA (0.46) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8646317 | 0.79 | TSHR (0.41) | TSHRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7485367 | 0.75 | TSHR (0.50) | TSHRKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |