SCHEMBL8600332

SCHEMBL8600332

CC(C)Nc1cc(Cl)nc(N)[n+]1[O-]

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CDK2 P24941 1/20 0.31
HRH4 Q9H3N8 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8598413 0.81
SCHEMBL9156151 0.80 ESR1 (0.42) TDP1HRH4
SCHEMBL14463130 0.77 CYP2D6 (0.31)
SCHEMBL8599188 0.77 KMT2A (0.33)
SCHEMBL8597280 0.77 LMNA (0.32)
SCHEMBL8602832 0.74 MAPT (0.38) HRH4
SCHEMBL10991551 0.73 MAPKAPK2 (0.35)
SCHEMBL8597239 0.72 TLR8 (0.40)
SCHEMBL14269189 0.71 CYP2D6 (0.50) GAACDK2HRH4
SCHEMBL8687196 0.71 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5772990-A Composition for slowing down the loss of hair based on pyrimidine N-oxides triaminosubstituted or their sulfoconjugated L'OREAL (FR) 1998-06-30 US disclosed