Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599188 | 0.83 | KMT2A (0.33) | SMN1; SMN2 | |
| SCHEMBL8602832 | 0.80 | MAPT (0.38) | HRH4SMN1; SMN2 | |
| SCHEMBL8600332 | 0.80 | GAA (0.32) | HRH4TDP1 | |
| SCHEMBL8597239 | 0.78 | TLR8 (0.40) | SMN1; SMN2 | |
| SCHEMBL8598413 | 0.77 | — | — | |
| SCHEMBL14269189 | 0.77 | CYP2D6 (0.50) | HRH4SMN1; SMN2 | |
| SCHEMBL7117925 | 0.75 | KMT2A (0.38) | — | |
| SCHEMBL7118888 | 0.75 | KMT2A (0.38) | — | |
| SCHEMBL7126475 | 0.75 | KMT2A (0.38) | — | |
| SCHEMBL14463130 | 0.74 | CYP2D6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466694-A | Hair growth regulators | L'OREAL (FR) | 1995-11-14 | — | — | US | disclosed |