Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 6/20 | 0.35 |
| ▸ | NPY1R | P25929 | 5/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798116 | 1.00 | DPP7 (0.37) | DPP7OTCALOX15MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5579459 | 0.98 | DPP7 (0.36) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL4810722 | 0.84 | DPP7 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL15820093 | 0.84 | DPP7 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL4810699 | 0.84 | DPP7 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL6680407 | 0.84 | NPY4R (0.46) | DPP7NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11814623 | 0.83 | OTC (0.41) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL2186467 | 0.83 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL2186462 | 0.83 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL8213398 | 0.83 | OTC (0.41) | DPP7OTCALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770699-A | ACYLATION | COR THERAPEUTICS, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5602233-A | ACTIVATION AND DEACTIVATION | COR THERAPEUTICS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5589572-A | Process for production of inhibited forms of activated blood factors | COR THERAPEUTICS, INC. (US) | 1996-12-31 | — | — | US | disclosed |
| US-5589571-A | Process for production of inhibited forms of activated blood factors | COR THERAPEUTICS, INC. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0489070-A1 | NOVEL INHIBITORS OF THROMBIN. | BIOGEN INC (US) | 1992-06-10 | — | — | EP | disclosed |
| US-4318904-A | ANTICOAGULANTS, THROMBIN INHIBITION | RESEARCH CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |