SCHEMBL8600509

SCHEMBL8600509

CCC[Mg]Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
IDO1 P14902 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CALM1 P0DP23 1/20 0.38
TSHR P16473 4/20 0.36
SIGMAR1 Q99720 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
TRPA1 O75762 1/20 0.35
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27987279 0.96 TP53 (0.42) TP53IDO1ALDH1A1HPGDALOX15
SCHEMBL8601778 0.86 TP53 (0.42) TP53IDO1SIGMAR1SMN1; SMN2
SCHEMBL8598271 0.85 SIGMAR1 (0.44) TP53SIGMAR1SMN1; SMN2
Hydrochloric Acid SCHEMBL23794958 0.85 TP53 (0.41) TP53SIGMAR1SMN1; SMN2
Iodide SCHEMBL11691633 0.85 TP53 (0.41) TP53IDO1SIGMAR1SMN1; SMN2
Hydrochloric Acid SCHEMBL28008613 0.83 MEN1 (0.41) TP53SIGMAR1SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL28182325 0.83 TP53 (0.39) TP53SIGMAR1SMN1; SMN2
SCHEMBL8602023 0.83 DNM1 (0.46) TP53SIGMAR1SMN1; SMN2
Hydrochloric Acid SCHEMBL15019401 0.83 SIGMAR1 (0.43) TP53SIGMAR1SMN1; SMN2
Hydrochloric Acid SCHEMBL28008614 0.83 TP53 (0.39) TP53SIGMAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571945-B1 Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst SUMITOMO CHEMICAL CO (JP) 1998-02-04 EP disclosed
US-5602223-A RADIATION TRANSPARENT, GLOSS, MELT TENSION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-11 US disclosed
US-5508364-A USING A ZIELGER CATALYST CONTAINING A TITANIUM COMPOUND WITH TITANIUM NITROGEN BOND, ORGANOMAGNESIUM AND ORGANOALUMINUM COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-16 US disclosed
EP-0588567-A1 An ethylene-alpha-olefin copolymer and a molded article therefrom SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-23 EP disclosed
EP-0571945-A2 Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-12-01 EP disclosed