SCHEMBL8600641

SCHEMBL8600641

CCN(CC)c1ccc(N2CCC=N2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 3/20 0.41
GFER P55789 2/20 0.41
GAA P10253 3/20 0.41
RAB9A P51151 2/20 0.41
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TP53 P04637 1/20 0.40
PSMD14 O00487 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 6/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 3/20 0.39
HTT P42858 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11401374 0.80 TP53 (0.47) TP53
SCHEMBL27771827 0.71 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AKDM4EGFER
SCHEMBL27291390 0.71 TP53 (0.42) ALDH1A1MEN1KMT2AKDM4EGFER
SCHEMBL17915946 0.70 TP53 (0.43) ALDH1A1MEN1KMT2AGAATSHR
SCHEMBL28239501 0.70 HTR3E (0.44) ALDH1A1KMT2AGAARAB9ATSHR
SCHEMBL44773 0.70 TP53 (0.48) MEN1KMT2AKDM4ERAB9ATDP1
SCHEMBL1735497 0.68 ALDH1A1 (0.74) ALDH1A1MEN1KMT2AKDM4EGFER
SCHEMBL27762333 0.68 TP53 (0.47) ALDH1A1MEN1KMT2AKDM4ERAB9A
SCHEMBL10825123 0.67 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AKDM4EGFER
SCHEMBL19562044 0.67 MAP4K1 (0.54) ALDH1A1MEN1KMT2AKDM4EGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821279-A1 Electrophotographic photoreceptor and coating solution for production of charge transport layer HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-01-28 EP disclosed
EP-0401782-A2 Titanyl phthalocyanine crystal, method of manufacture thereof and its use for electrophotographic photosensitive material NEC CORPORATION (JP) 1990-12-12 EP disclosed
EP-0368251-A2 Photosensitive material for electrophotography and method for making same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-05-16 EP disclosed
EP-0314100-A2 Alpha-type titanyl phthalocyanine composition, method for production thereof, and electrophotographic sensitive material using same MITA INDUSTRIAL CO. LTD. (JP) 1989-05-03 EP disclosed
US-4717636-A Electrophotographic photosensitive member containing polyvinylarylal CANON KABUSHIKI KAISHA (JP) 1988-01-05 US disclosed