Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401374 | 0.89 | TP53 (0.47) | TP53 | |
| SCHEMBL24527388 | 0.79 | ALOX5 (0.37) | TP53 | |
| SCHEMBL5402991 | 0.75 | TRIM24 (0.48) | TP53ALDH1A1MAPK1KDM4EMEN1 | |
| SCHEMBL17915946 | 0.75 | TP53 (0.43) | TP53ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL8600641 | 0.71 | ALDH1A1 (0.41) | TP53ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL11186135 | 0.67 | MEN1 (0.44) | TP53ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL10655726 | 0.66 | ADRA2C (0.47) | TP53ALDH1A1MAPTLMNATDP1 | |
| SCHEMBL7717944 | 0.64 | ABL1 (0.57) | TP53ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL20285407 | 0.64 | MEN1 (0.41) | TP53ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL4067323 | 0.64 | MAPT (0.50) | TP53ALDH1A1MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981864-B | N- (4-fluorophenyl) -4, 5-dihydropyrazole compound and application thereof in pesticide | 西华大学 | 2021-01-29 | — | — | CN | disclosed |
| CN-110981864-B | N- (4-fluorophenyl) -4, 5-dihydropyrazole compound and application thereof in pesticide | 西华大学 | 2021-01-29 | — | — | CN | disclosed |
| CN-110981864-B | N- (4-fluorophenyl) -4, 5-dihydropyrazole compound and application thereof in pesticide | 西华大学 | 2021-01-29 | — | — | CN | disclosed |
| CN-110981864-A | N- (4-fluorophenyl) -4, 5-dihydropyrazole compound and application thereof in pesticide | 西华大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-110981864-A | N- (4-fluorophenyl) -4, 5-dihydropyrazole compound and application thereof in pesticide | 西华大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-110981864-A | N- (4-fluorophenyl) -4, 5-dihydropyrazole compound and application thereof in pesticide | 西华大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-101312974-A | Pyrazoloisoquinoline derivatives | PALAU PHARMA SA (ES) | 2008-11-26 | — | — | CN | disclosed |
| CN-1004272-B | PYRAZOLINE INSECTICIDES | FMC公司 | 1989-05-24 | — | — | CN | disclosed |
| CN-85107882-A | Preparation method for pyrazolines | — | 1986-06-10 | — | — | CN | disclosed |