Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 11/20 | 0.48 |
| ▸ | HTR1D | P28221 | 10/20 | 0.47 |
| ▸ | HTR1A | P08908 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600111 | 1.00 | HTR1B (0.48) | HTR1BHTR1DHTR1AMAPTMAPK1 | |
| SCHEMBL8600892 | 1.00 | HTR1B (0.48) | HTR1BHTR1DHTR1AMAPTMAPK1 | |
| SCHEMBL8604139 | 0.90 | HTR1B (0.44) | HTR1BHTR1DHTR1AMAPTMAPK1 | |
| SCHEMBL8601916 | 0.84 | ALDH1A1 (0.53) | MAPTMAPK1TDP1TP53KDM4E | |
| SCHEMBL16134903 | 0.78 | ALDH1A1 (0.50) | HTR1BHTR1DHTR1AMAPTMAPK1 | |
| SCHEMBL8604181 | 0.77 | HTR1A (0.46) | HTR1BHTR1DHTR1ATP53KDM4E | |
| SCHEMBL8602835 | 0.77 | HTR1A (0.46) | HTR1BHTR1DHTR1ATP53KDM4E | |
| SCHEMBL11505407 | 0.77 | HDAC1 (0.61) | HTR1BHTR1DHTR1AMAPTMAPK1 | |
| SCHEMBL11788344 | 0.77 | HDAC1 (0.61) | HTR1BHTR1DHTR1AMAPTMAPK1 | |
| SCHEMBL17402429 | 0.77 | HDAC1 (0.61) | HTR1BHTR1DHTR1AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |