Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604139 | 0.88 | HTR1B (0.44) | ALDH1A1HPGDHSD17B10MAPTMEN1 | |
| SCHEMBL8600892 | 0.84 | HTR1B (0.48) | MAPTMEN1KMT2ATSHRKDM4E | |
| SCHEMBL8600658 | 0.84 | HTR1B (0.48) | MAPTMEN1KMT2ATSHRKDM4E | |
| SCHEMBL8600111 | 0.84 | HTR1B (0.48) | MAPTMEN1KMT2ATSHRKDM4E | |
| SCHEMBL8603460 | 0.81 | KMT2A (0.58) | ALDH1A1HPGDPSMB8HSD17B10MAPT | |
| SCHEMBL8602858 | 0.79 | IMPDH2 (0.56) | ALDH1A1HPGDMAPTKDM4ERAB9A | |
| SCHEMBL8601195 | 0.77 | KMT2A (0.38) | ALDH1A1HPGDHSD17B10MAPTMEN1 | |
| SCHEMBL8602828 | 0.77 | KIF11 (0.50) | ALDH1A1HPGDHSD17B10MAPTMEN1 | |
| SCHEMBL6626981 | 0.77 | MEN1 (0.61) | ALDH1A1HPGDHSD17B10MAPTESR2 | |
| SCHEMBL827340 | 0.76 | MEN1 (0.65) | ALDH1A1HPGDHSD17B10MAPTESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |