Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.51 |
| ▸ | MPL | P40238 | 2/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887694 | 0.91 | SRC (0.61) | APPSRCPRKACAPRKACGPRKACB | |
| SCHEMBL30143007 | 0.91 | SRC (0.61) | APPSRCPRKACAPRKACGPRKACB | |
| Acetic Acid SCHEMBL11537832 | 0.81 | MPL (0.51) | APPPARP14MPLFTOKIF11 | |
| Acetic Acid SCHEMBL27471236 | 0.78 | PARP14 (0.56) | APPPARP14MPLFTOKIF11 | |
| Carbazole SCHEMBL28171971 | 0.78 | ALDH1A1 (0.70) | KIF11MAPTCYP1A2POLBKDM4E | |
| Potassium Ion SCHEMBL10354598 | 0.78 | APP (0.52) | APPPARP14MPLFTOKIF11 | |
| SCHEMBL10354781 | 0.78 | APP (0.52) | APPPARP14MPLFTOKIF11 | |
| SCHEMBL17094777 | 0.77 | AR (0.58) | APPSRCPRKACAPRKACGPRKACB | |
| SCHEMBL5964419 | 0.77 | KIF11 (0.56) | APPPARP14MPLFTOKIF11 | |
| SCHEMBL14701007 | 0.77 | KIF11 (0.61) | APPPARP14MPLKIF11PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563287-B1 | METHODS, KITS AND REACTIVE SUPPORTS FOR 3' LABELING OF OLIGONUCLEOTIDES | ABBOTT LAB (US) | 1998-02-11 | — | — | EP | disclosed |
| EP-0563287-A4 | METHODS, KITS AND REACTIVE SUPPORTS FOR 3' LABELING OF OLIGONUCLEOTIDES | ABBOTT LAB (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0563287-A1 | METHODS, KITS AND REACTIVE SUPPORTS FOR 3' LABELING OF OLIGONUCLEOTIDES | ABBOTT LABORATORIES (US) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011388-A1 | METHODS, KITS AND REACTIVE SUPPORTS FOR 3' LABELING OF OLIGONUCLEOTIDES | ABBOTT LABORATORIES (US) | 1992-07-09 | — | — | WO | disclosed |