Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668475 | 0.78 | TDP1 (0.49) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8602043 | 0.77 | KDM4E (0.38) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL8599316 | 0.77 | KDM4E (0.36) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL8596779 | 0.76 | EGFR (0.38) | ALDH1A1MAPTLMNAKMT2AEGFR | |
| SCHEMBL8597055 | 0.75 | ALDH1A1 (0.36) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8599937 | 0.72 | MAPT (0.48) | ALDH1A1MAPTLMNAKMT2AEGFR | |
| SCHEMBL8595123 | 0.72 | EGFR (0.36) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8597271 | 0.72 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8601697 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8564866 | 0.71 | EGFR (0.41) | ALDH1A1MAPTLMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |