Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597975 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL8596770 | 0.74 | KMT2A (0.39) | ALDH1A1MAPTMAPK1LMNAHTT | |
| SCHEMBL22858571 | 0.74 | MAPT (0.44) | ALDH1A1MAPTMAPK1HTTRAB9A | |
| SCHEMBL8598894 | 0.73 | MEN1 (0.39) | ALDH1A1MAPTLMNAHTTRAB9A | |
| SCHEMBL8597271 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL5668475 | 0.73 | TDP1 (0.49) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8600759 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL5164284 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL27446164 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL8597959 | 0.70 | PDE10A (0.44) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |