Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | VCP | P55072 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302147 | 0.88 | NAMPT (0.54) | NAMPTNPC1MEN1KMT2AVCP | |
| SCHEMBL8600776 | 0.83 | EPHX1 (0.73) | NPC1RAB9AMEN1KMT2AVCP | |
| SCHEMBL8600781 | 0.83 | EPHX1 (0.73) | NPC1RAB9AMEN1KMT2AVCP | |
| SCHEMBL6302405 | 0.81 | EPHX1 (0.73) | NAMPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL14534739 | 0.79 | ALDH1A1 (0.54) | NAMPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3334590 | 0.79 | MGLL (0.52) | NAMPTVCPSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4798640 | 0.77 | VCP (0.50) | VCPSMN1; SMN2ALDH1A1 | |
| SCHEMBL10639382 | 0.77 | VCP (0.50) | VCPSMN1; SMN2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4804478 | 0.76 | VCP (0.49) | VCPSMN1; SMN2ALDH1A1 | |
| SCHEMBL9178993 | 0.75 | EPHX1 (0.84) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |