Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413929 | 0.90 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10TDP1CES2 | |
| SCHEMBL155434 | 0.87 | TSHR (0.68) | ALDH1A1TSHRHSD17B10TDP1POLB | |
| SCHEMBL29631091 | 0.87 | TSHR (0.68) | ALDH1A1TSHRHSD17B10TDP1POLB | |
| Benzene SCHEMBL12472151 | 0.85 | TSHR (0.71) | ALDH1A1TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL11655234 | 0.85 | TSHR (0.66) | ALDH1A1TSHRHSD17B10TDP1POLB | |
| SCHEMBL36252 | 0.82 | CES2 (0.62) | ALDH1A1TDP1CES2CES1POLB | |
| SCHEMBL7756852 | 0.82 | TSHR (0.58) | ALDH1A1TSHRHSD17B10TDP1POLB | |
| SCHEMBL27806654 | 0.81 | CES2 (0.52) | ALDH1A1CES2CES1ADRB2ADRB1 | |
| SCHEMBL2477857 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6055000 | 0.80 | TSHR (0.59) | ALDH1A1TSHRHSD17B10TDP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589386-B1 | Fluorosilicone rubber composition | DOW CORNING TORAY SILICONE (JP) | 1998-02-04 | — | — | EP | claimed |
| US-10385010-B1 | Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| CN-102933366-B | Integrated irradiation device | 迈图高新材料有限责任公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-102933366-A | Integrated irradiation device | MOMENTIVE PERFORMANCE MAT INC | 2013-02-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385010-B1 | Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction | TALDO1, DDO, DAO | ALDH1A1 346/4885TSHR 2270/4885HSD17B10 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.