Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | RRM2 | P31350 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638600 | 0.82 | MAPT (0.38) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL8596102 | 0.82 | HCAR3 (0.42) | MAPTALDH1A1HTTHCAR3RRM2 | |
| SCHEMBL2483154 | 0.80 | SMN1; SMN2 (0.46) | MAPTALDH1A1HTTHCAR3KMT2A | |
| SCHEMBL7697934 | 0.77 | MAPT (0.59) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL8568520 | 0.76 | BACE1 (0.56) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL8600198 | 0.76 | MAPT (0.58) | MAPTALDH1A1HTTHCAR3KMT2A | |
| SCHEMBL19897482 | 0.75 | MAPT (0.46) | MAPTALDH1A1HCAR3KMT2AL3MBTL1 | |
| SCHEMBL8597357 | 0.74 | ALDH1A1 (0.39) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL8600033 | 0.74 | HPGD (0.50) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL1344661 | 0.74 | HCAR3 (0.58) | MAPTALDH1A1HTTHCAR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |