Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600991 | 1.00 | RNPEP (0.36) | RNPEPSLC7A5ALDH1A1MMEMEN1 | |
| SCHEMBL16824154 | 0.79 | MMP8 (0.36) | RNPEPSLC7A5ALDH1A1MMEMEN1 | |
| SCHEMBL12136003 | 0.73 | RNPEP (0.46) | RNPEPSLC7A5ALDH1A1MEN1KMT2A | |
| SCHEMBL7197080 | 0.73 | DGAT1 (0.48) | ALDH1A1DGAT1 | |
| SCHEMBL30386311 | 0.71 | CTSS (0.37) | RNPEPSLC7A5ALDH1A1MMEMEN1 | |
| SCHEMBL20960951 | 0.71 | RNPEP (0.40) | RNPEPSLC7A5ALDH1A1MEN1KMT2A | |
| SCHEMBL14670248 | 0.71 | RNPEP (0.40) | RNPEPSLC7A5ALDH1A1MEN1KMT2A | |
| SCHEMBL606621 | 0.70 | DGAT1 (0.37) | ALDH1A1DGAT1 | |
| SCHEMBL21902741 | 0.70 | RNPEP (0.43) | RNPEPSLC7A5ALDH1A1MEN1KMT2A | |
| SCHEMBL28550395 | 0.70 | DGAT1 (0.37) | ALDH1A1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821669-A1 | HYDROXAMIC AND CARBOXYLIC ACIDS AS METALLOPROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| US-5691381-A | ANTAGONIST OF TUMOR NECROSIS FACTOR, ANTIINFLAMMATORY AGENT, ANTIARTHRITIC AGENT | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1996033166-A1 | HYDROXAMIC AND CARBOXYLIC ACIDS AS METALLOPROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |