Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.31 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254847 | 0.86 | L3MBTL1 (0.41) | L3MBTL1USP2LMNA | |
| SCHEMBL10029372 | 0.81 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL2744420 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL28374394 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL19810008 | 0.75 | ALDH1A1 (0.39) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL10029375 | 0.75 | MEN1 (0.41) | L3MBTL1ALDH1A1SLC13A5MAPTUSP2 | |
| SCHEMBL19810009 | 0.75 | ALDH1A1 (0.39) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL15806369 | 0.75 | MEN1 (0.41) | L3MBTL1ALDH1A1SLC13A5MAPTUSP2 | |
| SCHEMBL23330 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL232278 | 0.72 | L3MBTL1 (0.36) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821669-A1 | HYDROXAMIC AND CARBOXYLIC ACIDS AS METALLOPROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| US-5691381-A | ANTAGONIST OF TUMOR NECROSIS FACTOR, ANTIINFLAMMATORY AGENT, ANTIARTHRITIC AGENT | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1996033166-A1 | HYDROXAMIC AND CARBOXYLIC ACIDS AS METALLOPROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |