Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149795 | 0.90 | BACE1 (0.46) | HTR1ASLC6A4CA2TSHRCHRNA7 | |
| SCHEMBL4450281 | 0.87 | CA2 (0.48) | HTR1ASLC6A4CA2CHRNA7MAOA | |
| SCHEMBL4442733 | 0.86 | CA2 (0.47) | HTR1ASLC6A4CA2CHRNA7MAOA | |
| SCHEMBL4438841 | 0.86 | CA2 (0.47) | HTR1ASLC6A4CA2CHRNA7MAOA | |
| SCHEMBL4442739 | 0.86 | CA2 (0.47) | HTR1ASLC6A4CA2CHRNA7MAOA | |
| SCHEMBL4442755 | 0.86 | CA2 (0.47) | HTR1ASLC6A4CA2CHRNA7MAOA | |
| SCHEMBL8601229 | 0.86 | CA2 (0.47) | HTR1ASLC6A4CA2CHRNA7MAOA | |
| SCHEMBL4444144 | 0.85 | CA2 (0.46) | HTR1ASLC6A4CA2CHRNA7CYP1A2 | |
| SCHEMBL5756786 | 0.81 | HTR1A (0.43) | HTR1ASLC6A4CA2CHRNA7CYP1A2 | |
| SCHEMBL5758630 | 0.81 | HTR1A (0.43) | HTR1ASLC6A4CA2CHRNA7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |