Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 9/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601033 | 0.90 | HTR1A (0.41) | CA2HTR1ATSHRCHRNA7SLC6A4 | |
| SCHEMBL9151822 | 0.86 | BACE1 (0.53) | BACE1CA2HTR1APDE3BPDE3A | |
| SCHEMBL4450281 | 0.76 | CA2 (0.48) | BACE1CA2HTR1ACHRNA7SLC6A4 | |
| SCHEMBL4442733 | 0.75 | CA2 (0.47) | BACE1CA2HTR1ADYRK1ACHRNA7 | |
| SCHEMBL4442739 | 0.75 | CA2 (0.47) | BACE1CA2HTR1ADYRK1ACHRNA7 | |
| SCHEMBL8601229 | 0.75 | CA2 (0.47) | BACE1CA2HTR1ADYRK1ACHRNA7 | |
| SCHEMBL4438841 | 0.75 | CA2 (0.47) | BACE1CA2HTR1ADYRK1ACHRNA7 | |
| SCHEMBL4442755 | 0.75 | CA2 (0.47) | BACE1CA2HTR1ADYRK1ACHRNA7 | |
| SCHEMBL4444144 | 0.73 | CA2 (0.46) | BACE1CA2HTR1APDE3BPDE3A | |
| SCHEMBL5756786 | 0.70 | HTR1A (0.43) | CA2HTR1APDE3BPDE3ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| US-5449812-A | Substituted benzenesulfonamide derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-12 | — | — | US | disclosed |