Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333969 | 0.91 | CHEK2 (0.47) | CHEK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15233046 | 0.88 | IRAK4 (0.54) | CHEK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8604250 | 0.81 | HSP90AA1 (0.59) | CHEK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5559865 | 0.80 | MEN1 (0.47) | CHEK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5217725 | 0.79 | CHEK2 (0.87) | CHEK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14224669 | 0.78 | MEN1 (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8604368 | 0.76 | CHEK2 (0.61) | CHEK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7471355 | 0.75 | MAPT (0.43) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8601035 | 0.75 | KMT2A (0.43) | CHEK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8600314 | 0.75 | CHEK2 (0.60) | CHEK2NPC1RAB9AMAPTNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |