Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333969 | 0.83 | CHEK2 (0.47) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7471355 | 0.81 | MAPT (0.43) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL5559865 | 0.80 | MEN1 (0.47) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7473157 | 0.79 | MAPT (0.43) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7470258 | 0.78 | HPGD (0.46) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7465939 | 0.78 | MAPT (0.43) | KMT2AMEN1MAPTPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL7462715 | 0.78 | MAPT (0.42) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7477278 | 0.77 | MAPT (0.42) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL7462181 | 0.76 | ALDH1A1 (0.51) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL7468134 | 0.76 | MAPT (0.49) | KMT2AMEN1MAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |