Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835861 | 0.80 | SMN1; SMN2 (0.44) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8596783 | 0.77 | HTT (0.40) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8567672 | 0.76 | MEN1 (0.60) | MAPTKMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8596428 | 0.75 | GPR84 (0.44) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3874226 | 0.75 | MEN1 (0.36) | MAPTKMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL8600916 | 0.74 | MEN1 (0.61) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8599537 | 0.72 | KMT2A (0.36) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8599698 | 0.71 | KMT2A (0.43) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8597309 | 0.71 | KMT2A (0.38) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8600118 | 0.71 | MEN1 (0.33) | MAPTKMT2ASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |