Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599491 | 0.79 | HIF1A (0.39) | KMT2AATMGSK3AGSK3BHTT | |
| SCHEMBL8603232 | 0.77 | GSK3A (0.45) | KMT2AATMGSK3AGSK3BHTT | |
| SCHEMBL8562625 | 0.76 | HTT (0.67) | HTTLMNAALDH1A1NPC1MAPT | |
| SCHEMBL8599362 | 0.76 | SMN1; SMN2 (0.43) | KMT2AHTTLMNACCNA2CDK2 | |
| SCHEMBL25167946 | 0.75 | LMNA (0.43) | KMT2AHTTLMNAALDH1A1NPC1 | |
| SCHEMBL8597635 | 0.75 | L3MBTL1 (0.49) | KMT2AHTTLMNAALDH1A1NPC1 | |
| SCHEMBL3874226 | 0.75 | MEN1 (0.36) | KMT2AHTTLMNAALDH1A1NPC1 | |
| SCHEMBL113131 | 0.74 | GSK3A (0.46) | KMT2AATMGSK3AGSK3BLMNA | |
| SCHEMBL8600198 | 0.74 | MAPT (0.58) | KMT2AHTTLMNAALDH1A1NPC1 | |
| SCHEMBL8601717 | 0.73 | ALDH1A1 (0.36) | KMT2AATMGSK3AGSK3BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |