Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599148 | 0.77 | HASPIN (0.41) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL8568938 | 0.74 | GSTP1 (0.49) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8598691 | 0.74 | IMPDH2 (0.32) | KMT2AMAPTMEN1USP2KEAP1 | |
| SCHEMBL8566844 | 0.73 | MEN1 (0.40) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8601170 | 0.72 | MAPT (0.38) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8596783 | 0.72 | HTT (0.40) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8595244 | 0.72 | KMT2A (0.39) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8597271 | 0.72 | ALDH1A1 (0.34) | MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8597903 | 0.71 | GSK3A (0.41) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8595123 | 0.70 | EGFR (0.36) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |