Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603167 | 0.97 | KCNH2 (0.38) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL8601318 | 0.89 | CYP3A4 (0.38) | KCNH2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL195696 | 0.84 | HTR7 (0.34) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL5156866 | 0.81 | CDK1 (0.35) | KCNH2TLR8TLR7CDK1CCNB1 | |
| SCHEMBL15438151 | 0.77 | KCNH2 (0.34) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL9613742 | 0.77 | KCNH2 (0.34) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL8523821 | 0.76 | KCNH2 (0.33) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL27642131 | 0.76 | TSHR (0.35) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL8603182 | 0.75 | NPC1 (0.31) | NPC1 | |
| SCHEMBL9197534 | 0.74 | HTR7 (0.33) | HTR7ADRA1DADRA1AADRA1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698627-B1 | Aminoplast resins and their use as a crosslinker of cellulose | HOECHST FRANCE (FR) | 1998-03-04 | — | — | EP | claimed |
| US-5665851-A | Aminoplastic resins and their use as a crosslinking agent for cellulose | SEQUA CHEMICALS, INC. (US) | 1997-09-09 | — | — | US | claimed |
| US-5665851-A | Aminoplastic resins and their use as a crosslinking agent for cellulose | SEQUA CHEMICALS, INC. (US) | 1997-09-09 | — | — | US | disclosed |