SCHEMBL195696

SCHEMBL195696

CCCCOC(O)Nc1nc(N)nc(N)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 5/20 0.34
KCNH2 Q12809 3/20 0.34
ADRA1D P25100 2/20 0.34
ADRA1A P35348 2/20 0.34
ADRA1B P35368 2/20 0.34
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CCNA1 P78396 1/20 0.33
PIN1 Q13526 1/20 0.33
TLR8 Q9NR97 5/20 0.32
TLR7 Q9NYK1 3/20 0.32
LMNA P02545 2/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
GLA P06280 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9197534 0.90 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL8601291 0.84 KCNH2 (0.38) HTR7KCNH2ADRA1DADRA1AADRA1B
SCHEMBL5156866 0.83 CDK1 (0.35) HTR7KCNH2ADRA1DADRA1AADRA1B
SCHEMBL4363447 0.83 NPSR1 (0.47) ADORA1
SCHEMBL9014254 0.83 MEN1 (0.34) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL8603167 0.81 KCNH2 (0.38) HTR7KCNH2ADRA1DADRA1AADRA1B
SCHEMBL9613742 0.79 KCNH2 (0.34) HTR7KCNH2ADRA1DADRA1AADRA1B
SCHEMBL15438151 0.79 KCNH2 (0.34) HTR7KCNH2ADRA1DADRA1AADRA1B
SCHEMBL8523821 0.78 KCNH2 (0.33) HTR7KCNH2ADRA1DADRA1AADRA1B
SCHEMBL27642131 0.78 TSHR (0.35) HTR7KCNH2ADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4320172-A Organopolysiloxane resin compositions for release papers SHIN-ETSU CHEMICAL CO., LTD. (JP) 1982-03-16 US claimed
JP-7331167-A None JP disclosed
US-12559620-B2 Curable coating compositions PPG INDUSTRIES OHIO, INC. (US) 2026-02-24 US disclosed
US-20230272209-A1 CURABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2023-08-31 US disclosed
US-20220221790-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ORGANIC EL ELEMENT PARTITION WALL SHOWA DENKO K.K. (JP) 2022-07-14 US disclosed
CN-111433252-B Polyester resin, aqueous polyester resin dispersion, and method for producing aqueous polyester resin dispersion 东洋纺株式会社 2022-06-14 CN disclosed
US-20220177754-A1 CURABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2022-06-09 US disclosed
WO-2022010972-A1 CURABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2022-01-13 WO disclosed
CN-113892057-A Photosensitive resin composition and organic EL element partition wall 昭和电工株式会社 2022-01-04 CN disclosed
CN-111433252-A Polyester resin, aqueous polyester resin dispersion, and method for producing aqueous polyester resin dispersion 东洋纺株式会社 2020-07-17 CN disclosed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP disclosed
US-5039343-A Water borne metallic coating composition NIPPON PAINT CO., LTD. (JP) 1991-08-13 US disclosed
EP-0393579-A1 Water borne metallic coating composition NIPPON PAINT CO., LTD. (JP) 1990-10-24 EP disclosed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US disclosed
US-4812335-A METALLIC PIGMENT, WET-ON-WET, TWO-COAT, ONE-BAKE NIPPON PAINT CO., LTD. (JP) 1989-03-14 US disclosed
EP-0266152-A2 Method of painting Nippon Paint Co., Ltd. (JP) 1988-05-04 EP disclosed
EP-0177122-A2 Acrylamide derivatives Nippon Paint Co., Ltd. (JP) 1986-04-09 EP disclosed
US-4515849-A Transfer printing sheet, printing method and printed article MATSUI SHIKISO CHEMICAL CO. LTD. (JP) 1985-05-07 US disclosed
US-4320172-A Organopolysiloxane resin compositions for release papers SHIN-ETSU CHEMICAL CO., LTD. (JP) 1982-03-16 US disclosed
US-4128437-A ESTER ALKYLENE ETHERS OF BISPHENOL A SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559620-B2 Curable coating compositions ESD, EPHX2, EED HTR7 2935/4885KCNH2 2406/4885ADRA1D 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.