SCHEMBL15438151

SCHEMBL15438151

CCCCOC(CCC)Nc1nc(N)nc(N)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.34
CYP2D6 P10635 1/20 0.33
DRD1 P21728 1/20 0.33
HTR2A P28223 1/20 0.33
ADORA1 P30542 1/20 0.33
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CCNA1 P78396 1/20 0.33
PIN1 Q13526 1/20 0.33
HTR7 P34969 5/20 0.32
ADRA1D P25100 2/20 0.32
ADRA1A P35348 2/20 0.32
ADRA1B P35368 2/20 0.32
TLR8 Q9NR97 4/20 0.32
TLR7 Q9NYK1 3/20 0.32
HTT P42858 2/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15437963 0.90 LMNA (0.33) KCNH2CYP2D6DRD1HTR2AADORA1
SCHEMBL8523821 0.86 KCNH2 (0.33) KCNH2CYP2D6DRD1HTR2AADORA1
SCHEMBL15437996 0.85 MEN1 (0.33) KCNH2CYP2D6DRD1HTR2AADORA1
SCHEMBL5156866 0.82 CDK1 (0.35) KCNH2CDK1CCNB1CCNA2CDK2
SCHEMBL6754311 0.80 CYP2D6 (0.35) KCNH2CYP2D6DRD1HTR2AADORA1
SCHEMBL195696 0.79 HTR7 (0.34) KCNH2CYP2D6DRD1HTR2AADORA1
SCHEMBL9613742 0.78 KCNH2 (0.34) KCNH2CYP2D6DRD1HTR2AADORA1
SCHEMBL11368962 0.78 TLR8 (0.38) KCNH2HTR7TLR8TLR7
SCHEMBL8601291 0.77 KCNH2 (0.38) KCNH2CYP2D6DRD1HTR2AADORA1
SCHEMBL28425316 0.75 CYP2D6 (0.33) KCNH2CYP2D6DRD1HTR2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113597455-B Water-based coating composition and coated metal sheet 日本制铁株式会社 2023-01-06 CN disclosed
CN-113597455-A Coating composition and coated metal sheet 日本制铁株式会社 2021-11-02 CN disclosed
WO-2020194799-A1 COATING MATERIAL COMPOSITION AND COATED METAL SHEET 日鉄日新製鋼株式会社 2020-10-01 WO disclosed
US-20140037950-A1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2014-02-06 US disclosed
US-20140037911-A1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2014-02-06 US disclosed
US-20140030511-A1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2014-01-30 US disclosed