SCHEMBL8601416

SCHEMBL8601416

NCCCCCCNc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.61
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
EGFR P00533 2/20 0.61
MAPK1 P28482 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
ALDH1A1 P00352 2/20 0.61
HTT P42858 2/20 0.61
POLB P06746 2/20 0.61
BLM P54132 2/20 0.61
LMNA P02545 1/20 0.61
RAD52 P43351 1/20 0.61
RECQL P46063 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
NSD2 O96028 2/20 0.56
FGB P02675 1/20 0.56
MMP14 P50281 1/20 0.56
TERT O14746 1/20 0.52
TDP1 Q9NUW8 8/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32667983 1.00 MAPT (0.61) MAPTMEN1KMT2ASMN1; SMN2EGFR
Hydrochloric Acid SCHEMBL8604068 0.99 MAPT (0.60) MAPTMEN1KMT2ASMN1; SMN2EGFR
SCHEMBL8602072 0.98 MAPT (0.63) MAPTMEN1KMT2ASMN1; SMN2EGFR
Hydrochloric Acid SCHEMBL8603274 0.97 MAPT (0.61) MAPTMEN1KMT2ASMN1; SMN2EGFR
SCHEMBL6372356 0.95 NSD2 (0.60) MAPTMEN1KMT2ASMN1; SMN2EGFR
SCHEMBL6366937 0.94 TERT (0.57) MAPTMEN1KMT2ASMN1; SMN2EGFR
SCHEMBL20333883 0.94 TERT (0.57) MAPTMEN1KMT2ASMN1; SMN2EGFR
SCHEMBL109325 0.94 MEN1 (0.64) MAPTMEN1KMT2ASMN1; SMN2EGFR
SCHEMBL6368226 0.94 NSD2 (0.61) MAPTMEN1KMT2ASMN1; SMN2EGFR
Hydrochloric Acid SCHEMBL6577424 0.93 MAPT (0.63) MAPTMEN1KMT2ASMN1; SMN2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948738-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS BASF SE (DE) 2018-02-28 EP disclosed
US-8456733-B2 Coloured particles for electrophoretic displays BASF SE (DE) 2013-06-04 US disclosed
US-8456733-B2 Coloured particles for electrophoretic displays BASF SE (DE) 2013-06-04 US disclosed
US-7947848-B2 Coloured silsesquioxanes BASF SE (DE) 2011-05-24 US disclosed
US-7947848-B2 Coloured silsesquioxanes BASF SE (DE) 2011-05-24 US disclosed
US-20090296195-A1 Coloured Particles for Electrophoretic Displays BASF SE (DE) 2009-12-03 US disclosed
US-20090296195-A1 Coloured Particles for Electrophoretic Displays BASF SE (DE) 2009-12-03 US disclosed
US-20090203931-A1 Coloured Silsesquioxanes BASF SE (DE) 2009-08-13 US disclosed
WO-2007147742-A1 COLOURED SILSESQUIOXANES CIBA HOLDING INC. (CH) 2007-12-27 WO disclosed
EP-0721447-B1 ANTHRACENE DERIVATIVES FOR USE AS ANTICANCER AGENT OR DYE UNIV NAPIER (GB) 1998-02-25 EP disclosed
EP-0721447-A1 ANTHRACENE DERIVATIVES FOR USE AS ANTICANCER AGENT OR DYE NAPIER UNIVERSITY VENTURES LIMITED (GB) 1996-07-17 EP disclosed
WO-1995009149-A1 ANTHRACENE DERIVATIVES FOR USE AS ANTICANCER AGENT OR DYE NAPIER UNIVERSITY VENTURES LIMITED (GB) 1995-04-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090296195-A1 Coloured Particles for Electrophoretic Displays RAB5IF, IK, AOX1 MAPT 4267/4885MEN1 3454/4885KMT2A 3839/4885
US-20090203931-A1 Coloured Silsesquioxanes CBX7, CD47, SFXN1 MAPT 2448/4885MEN1 4570/4885KMT2A 2327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.