Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599210 | 0.96 | — | — | |
| SCHEMBL8603150 | 0.84 | ALDH1A1 (0.33) | HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL8601360 | 0.83 | — | — | |
| SCHEMBL8602688 | 0.82 | MAPT (0.37) | HPGDSMN1; SMN2LMNAMAPTPOLB | |
| SCHEMBL8603023 | 0.82 | NPC1 (0.33) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL8602235 | 0.81 | KDM4E (0.33) | LMNA | |
| SCHEMBL8602392 | 0.81 | APP (0.35) | — | |
| SCHEMBL8601390 | 0.81 | CYP19A1 (0.36) | PTGS1PTGS2CYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL8601518 | 0.80 | PPOX (0.45) | PTGS1PTGS2CYP19A1HPGDSMN1; SMN2 | |
| SCHEMBL8602264 | 0.79 | ESR1 (0.35) | HPGDSMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |