Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 6/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602458 | 0.96 | PPOX (0.44) | PPOXSCN9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL8603603 | 0.83 | MAPT (0.39) | PPOXHPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL8599592 | 0.82 | PPOX (0.38) | PPOXHPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL8600830 | 0.81 | PPOX (0.51) | PPOXHPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL8599002 | 0.81 | SCN9A (0.34) | PPOXSCN9AHPGDPOLBSMN1; SMN2 | |
| SCHEMBL8599137 | 0.81 | KDM4E (0.42) | PPOXHPGDPTGDR2PTGDRGAA | |
| SCHEMBL8598865 | 0.81 | PPOX (0.37) | PPOXHPGD | |
| SCHEMBL8601499 | 0.80 | PTGS1 (0.32) | PPOXHPGDPOLBPTGS1PTGS2 | |
| SCHEMBL8603210 | 0.80 | PPOX (0.49) | PPOXSCN9AHPGDPOLBPTGS1 | |
| SCHEMBL8600214 | 0.79 | PPOX (0.44) | PPOXHPGDSMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |