SCHEMBL8601605

SCHEMBL8601605

COc1ncnc(OC)c1N=C=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
APLNR P35414 1/20 0.33
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27465167 0.76 ALDH1A1 (0.41) GABRA1GABRB2ALDH1A1CYP3A4HPGD
SCHEMBL11799618 0.69 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL27499839 0.64 KMT2A (0.46) ALDH1A1CYP3A4HPGDTDP1MAPT
SCHEMBL3817132 0.64 PDPK1 (0.45) PDPK1ALDH1A1HPGDMAPTMEN1
SCHEMBL1021667 0.64 GABRA1 (0.50) GABRA1GABRB2ALDH1A1CYP3A4HPGD
SCHEMBL6312320 0.63 ALDH1A1 (0.33) ALDH1A1CYP3A4HPGDTDP1
SCHEMBL19978863 0.63 PDPK1 (0.33) PDPK1MAPT
SCHEMBL9852982 0.62 PDPK1 (0.43) PDPK1ALDH1A1HPGDMAPTMEN1
SCHEMBL28463300 0.62 PDPK1 (0.43) PDPK1ALDH1A1HPGDMAPTMEN1
SCHEMBL30559720 0.62 PDPK1 (0.43) PDPK1ALDH1A1CYP3A4HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776858-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-07-07 US disclosed
EP-0771797-A1 1-Azinyl-tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1997-05-07 EP disclosed