Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496069 | 0.85 | PDPK1 (0.38) | PDPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18809342 | 0.79 | PDPK1 (0.34) | PDPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19489074 | 0.79 | PDPK1 (0.34) | PDPK1ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL13472337 | 0.77 | KMO (0.49) | PDPK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13472336 | 0.76 | NPSR1 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9044468 | 0.75 | ALDH1A1 (0.39) | PDPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3921763 | 0.75 | ALDH1A1 (0.39) | PDPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6796490 | 0.74 | PDPK1 (0.45) | PDPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3817132 | 0.74 | PDPK1 (0.45) | PDPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31718356 | 0.74 | ALDH1A1 (0.38) | PDPK1MAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419831-A2 | Substituted sulfonylaminoazoles | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |