Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.47 |
| ▸ | FABP3 | P05413 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989764 | 0.76 | FABP4 (0.69) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL9498373 | 0.73 | FABP4 (0.47) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL9014752 | 0.73 | FABP4 (0.47) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL6893855 | 0.71 | — | — | |
| SCHEMBL4781465 | 0.70 | FABP4 (0.41) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL22002825 | 0.69 | — | — | |
| SCHEMBL11074083 | 0.69 | PDE4B (0.41) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL9496309 | 0.68 | FABP4 (0.49) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL2946584 | 0.68 | FABP4 (0.62) | FABP4FABP3FABP5ALDH1A1GAA | |
| SCHEMBL162818 | 0.67 | FABP4 (0.67) | FABP4FABP3FABP5ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4373071-A | RESIN SUPPORTS; GENETIC ENGINEERING | CITY OF HOPE RESEARCH INSTITUTE (US) | 1983-02-08 | — | — | US | claimed |
| US-5750380-A | DNA polymerase mediated synthesis of double stranded nucleic acids | CITY OF HOPE RESEARCH INSTITUTE (US) | 1998-05-12 | — | — | US | disclosed |
| US-5583013-A | EXPRESSION IN A MICROORGANISM TRANSFORMED WITH A REPLICABLE CLONING VEHICLE; ENCODING DNA IS UNDER THE OPERATIVE CONTROL OF AN EXPRESSION CONTROL REGION | GENENTECH, INC. (US) | 1996-12-10 | — | — | US | disclosed |
| US-5548076-A | CONDENSING A BLOCKED NUCLEOSIDE BOUND TO A CARRIER | GENENTECH, INC. (US) | 1996-08-20 | — | — | US | disclosed |
| US-5420020-A | Method and means for microbial polypeptide expression | GENENTECH, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0219342-B1 | Method and reagents for in vitro oligonucleotide synthesis | GENENTECH INC (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5264566-A | Method for in vitro oligonucleotide synthesis using H-phosphonates | GENENTECH, INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-5221619-A | Expressing in microorganism transformed with replicable cloning vehicle comprising DNA encoding polypeptide under control of homologous region, recovering from cell culture | GENENTECH, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0159123-B1 | VECTORS FOR EXPRESSING BOVINE GROWTH HORMONE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |
| US-4968788-A | DRUG DELIVERY, ANTITUMOR AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-11-06 | — | — | US | disclosed |
| US-4366246-A | Method for microbial polypeptide expression | GENENTECH, INC. (US) | 1982-12-28 | — | — | US | disclosed |
| US-4356270-A | Recombinant DNA cloning vehicle | GENENTECH, INC. (US) | 1982-10-26 | — | — | US | disclosed |
| EP-0062971-A2 | Genetically modified microorganisms | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-10-20 | — | — | EP | disclosed |
| EP-0049619-A2 | Method for stabilizing and selecting host cells containing recombinant DNA | ELI LILLY AND COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4310662-A | Nucleosidic phosphorylating agent and methods | GENENTECH, INC. (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0035454-A2 | Desacetylthymosin alpha 1, its process of preparation and its use | GENENTECH, INC. (US) | 1981-09-09 | — | — | EP | disclosed |
| EP-0002322-A2 | Improved Triester process for the synthesis of oligonucleotides | GENENTECH, INC. (US) | 1979-06-13 | — | — | EP | disclosed |
| EP-0001931-A2 | Synthetic DNA, process for preparing it and recombinant microbial cloning vehicle containing such DNA | GENENTECH, INC. (US) | 1979-05-16 | — | — | EP | disclosed |
| EP-0001929-A2 | Plasmid for transforming bacterial host to render it capable of polypeptide expression | GENENTECH, INC. (US) | 1979-05-16 | — | — | EP | disclosed |
| EP-0001930-A2 | Method for polypeptide production involving expression of a heterologous gene, recombinant microbial cloning vehicle containing said gene and bacterial culture transformed by said cloning vehicle | GENENTECH, INC. (US) | 1979-05-16 | — | — | EP | disclosed |