⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10342580 | 0.79 | HSD11B1 (0.41) | — | |
| SCHEMBL8659577 | 0.76 | MEN1 (0.32) | — | |
| SCHEMBL9014773 | 0.74 | — | — | |
| SCHEMBL10343217 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL7268288 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL10435622 | 0.70 | L3MBTL1 (0.31) | — | |
| SCHEMBL2254706 | 0.69 | BTK (0.33) | — | |
| SCHEMBL971368 | 0.69 | L3MBTL1 (0.32) | — | |
| SCHEMBL10980384 | 0.68 | L3MBTL1 (0.32) | — | |
| SCHEMBL216708 | 0.68 | TRPV4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526912-B1 | Methods for the detection of a single-stranded target genetic material | ENZO BIOCHEM INC (US) | 2004-01-21 | — | — | EP | disclosed |
| US-20020031769-A1 | Processes for detecting polynucleotides, determining genetic mutations or defects in genetic material, separating or isolating nucleic acid of interest from samples, and useful compositions of matter and multi-hybrid complex compositions | ENZO DIAGNOSTICS, INC. | 2002-03-14 | — | — | US | disclosed |
| US-6221581-B1 | Processes for detecting polynucleotides, determining genetic mutations or defects in genetic material, separating or isolating nucleic acid of interest from samples, and useful compositions of matter and multihybrid complex compositions | ENZO DIAGNOSTICS, INC. | 2001-04-24 | — | — | US | disclosed |
| US-5807837-A | ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL | SANKYO COMPANY, LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5674856-A | TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS | SANKYO COMPANY, LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0611075-B1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5561225-A | Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages | SOUTHERN RESEARCH INSTITUTE (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0611075-A1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5288609-A | Capture sandwich hybridization method and composition | ENZO DIAGNOSTICS, INC. (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0159719-B1 | HYBRIDIZATION METHOD FOR THE DETECTION OF GENETIC MATERIALS | ENZO BIOCHEM, INC. (US) | 1993-06-30 | — | — | EP | disclosed |
| EP-0526912-A2 | Methods and compositions for the detection of a single-stranded target genetic material | ENZO BIOCHEM, INC. (US) | 1993-02-10 | — | — | EP | disclosed |
| US-4894325-A | Hybridization method for the detection of genetic material | ENZO BIOCHEM, INC. (US) | 1990-01-16 | — | — | US | disclosed |
| US-4738928-A | GENETIC ENGINEERING | YALE UNIVERSITY (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0159719-A2 | Hybridization method for the detection of genetic materials | ENZO BIOCHEM, INC. (US) | 1985-10-30 | — | — | EP | disclosed |
| US-4394443-A | Method for cloning genes | YALE UNIVERSITY (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0067213-A1 | METHOD FOR CLONING GENES | YALE UNIVERSITY (US) | 1982-12-22 | — | — | EP | disclosed |
| WO-1982002060-A1 | METHOD FOR CLONING GENES | UNIV YALE (US) | 1982-06-24 | — | — | WO | disclosed |