Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.47 |
| ▸ | FABP3 | P05413 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989764 | 0.76 | FABP4 (0.69) | FABP4FABP3FABP5TDP1GAA | |
| SCHEMBL10416063 | 0.74 | NAMPT (0.39) | TDP1ALDH1A1TXNRD1TAAR1ADRA2A | |
| SCHEMBL8601736 | 0.73 | FABP4 (0.47) | FABP4FABP3FABP5TDP1GAA | |
| SCHEMBL502541 | 0.72 | TXNRD1 (0.44) | ALDH1A1TXNRD1TAAR1 | |
| SCHEMBL4735410 | 0.71 | RAPGEF4 (0.44) | TDP1ALDH1A1TXNRD1 | |
| SCHEMBL9496309 | 0.71 | FABP4 (0.49) | FABP4FABP3FABP5TDP1GAA | |
| Bromide SCHEMBL28322202 | 0.70 | TXNRD1 (0.43) | ALDH1A1TXNRD1 | |
| SCHEMBL9498373 | 0.70 | FABP4 (0.47) | FABP4FABP3FABP5TDP1GAA | |
| SCHEMBL7974947 | 0.69 | FABP4 (0.46) | FABP4FABP3FABP5TDP1GAA | |
| SCHEMBL2946584 | 0.68 | FABP4 (0.62) | FABP4FABP3FABP5TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336756-A | A kind of hydrogenation-dehalogenation method of halogenated aromatic | 河南大学 | 2019-02-15 | — | — | CN | claimed |
| CN-103497149-A | Preparation method of 5-aminomethyl pyridine derivative | RENNOTECH CO LTD | 2014-01-08 | — | — | CN | claimed |
| CN-109336756-B | Hydrogenation dehalogenation method of halogenated aromatic hydrocarbon | 河南大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-109336756-A | A kind of hydrogenation-dehalogenation method of halogenated aromatic | 河南大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-103497149-A | Preparation method of 5-aminomethyl pyridine derivative | RENNOTECH CO LTD | 2014-01-08 | — | — | CN | disclosed |
| US-5561225-A | Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages | SOUTHERN RESEARCH INSTITUTE (US) | 1996-10-01 | — | — | US | disclosed |
| WO-1993024468-A1 | PYRIMIDINYL- AND TRIAZINYL- SALICYL- AND PICOLYLAMIDES AND THE USE, AS HERBICIDES, AND PREPARATION THEREOF | CIBA-GEIGY AG (CH) | 1993-12-09 | — | — | WO | disclosed |
| EP-0331032-B1 | 2'-DEOXY-5-FLUOROURIDINE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5032680-A | Antitumor | KURARAY CO., LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0331032-A1 | 2'-Deoxy-5-fluorouridine derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4677211-A | Preparation of lactones | SANDOZ PHARMACEUTICALS CORP. (US) | 1987-06-30 | — | — | US | disclosed |
| US-4625039-A | 4-trisubstituted silyl protected hydroxy-6-oxo-tetrahydropyran-2-yl-aldehyde intermediates | SANDOZ PHARM. CORP. (US) | 1986-11-25 | — | — | US | disclosed |
| US-4605645-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1986-08-12 | — | — | US | disclosed |
| EP-0081386-B1 | 5-FLUORO-2'-DEOXYURIDINE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | TEIJIN LIMITED (JP) | 1985-05-29 | — | — | EP | disclosed |
| US-4474971-A | ANTICHOLESTEROL AGENTS, ATHEROSCLEROSIS | SANDOZ, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0081386-A1 | 5-Fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof | TEIJIN LIMITED (JP) | 1983-06-15 | — | — | EP | disclosed |