SCHEMBL8601738

SCHEMBL8601738

C=CCS(=O)(=O)c1ccnc(N)c1[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 3/20 0.37
HTT P42858 6/20 0.36
MAPT P10636 4/20 0.36
MITF O75030 1/20 0.36
NPY1R P25929 7/20 0.35
NOD2 Q9HC29 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MGMT P16455 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TP53 P04637 2/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625607 0.81 CA12 (0.35) KDM4ELMNAHTTMAPTMITF
SCHEMBL8602563 0.81 ALDH1A1 (0.42) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL8598387 0.80 KDM4E (0.38) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL8601525 0.80 KMT2A (0.36) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL11630762 0.79 MAPT (0.38) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL8601717 0.78 ALDH1A1 (0.36) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL8568115 0.77 MAPT (0.42) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL8566342 0.77 ALDH1A1 (0.48) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL8560999 0.76 HTT (0.41) ALDH1A1KDM4ELMNAHTTMAPT
SCHEMBL8600998 0.76 TXNRD1 (0.43) ALDH1A1KDM4ELMNAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735025-B1 Process for producing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1998-07-01 EP disclosed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed
US-4087432-A HERBICIDES ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed
US-3968116-A HERBICIDE ELI LILLY AND COMPANY (US) 1976-07-06 US disclosed
US-3963734-A HERBICIDES, HERBICIDE INTERMEDIATES ELI LILLY AND COMPANY (US) 1976-06-15 US disclosed